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STEPS: Bromocriptine Mesylate (Cycloset) for Type 2 Diabetes ...

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May 15, 2013 - Cycloset will lower A1C levels by 0.3 to 0.5 percent when taken alone or in combination with a sulfonylurea, without undesirable adverse effects such as hypoglycemia and weight gain. It will not cause further ...

www.aafp.org/afp/2013/0515/p718.html

STEPS: Fidaxomicin (Dificid) for Clostridium difficile Infection ...

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Feb 1, 2013 - Fidaxomicin is effective for the treatment of C. difficile infection, but it is much more expensive than traditional therapy. Until it is known that the benefits outweigh the significant cost, metronidazole or oral ...

www.aafp.org/afp/2013/0201/p211.html

STEPS: Linagliptin (Tradjenta) for the Treatment of Diabetes ...

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Dec 15, 2012 - Linagliptin reduces A1C levels to a lesser extent than first-line therapy (metformin) and is significantly more expensive than metformin and sulfonylureas. Importantly, its ability to affect diabetes-related morbidity...

www.aafp.org/afp/2012/1215/p1144.html

STEPS: Rivaroxaban (Xarelto) for Prevention of Thromboembolic ...

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Oct 15, 2012 - In patients at high risk of stroke because of nonvalvular atrial fibrillation, rivaroxaban is as safe and effective as warfarin. However, it should not be used in patients at risk of stroke for reasons other than ...

www.aafp.org/afp/2012/1015/p768.html

STEPS: Ulipristal (Ella) for Emergency Contraception - August 15,...

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Aug 15, 2012 - Ulipristal is a prescription-only emergency contraceptive. It is at least as effective as levonorgestrel when administered within 72 hours of unprotected sexual intercourse, and is more effective than levonorgestrel ...

www.aafp.org/afp/2012/0815/p365.html

STEPS: Dutasteride/Tamsulosin (Jalyn) for Benign Prostatic ...

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Jun 15, 2012 - Jalyn offers the convenience of taking one medication instead of two. Although monotherapy with dutasteride or tamsulosin is beneficial for many men, the combination drug is slightly better than either component alone...

www.aafp.org/afp/2012/0615/p1194.html

STEPS: Tapentadol (Nucynta) for Treatment of Pain - May 1, 2012 -...

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May 1, 2012 - Tapentadol is a DEA schedule II opioid medication with a safety profile, duration of action, frequency of dosing, and analgesic effect similar to those of other oral narcotics, although it is more expensive. At low ...

www.aafp.org/afp/2012/0501/p910.html

STEPS: Denosumab (Prolia) for Treatment of Postmenopausal ...

Feb 15, 2012 - Prolia is an expensive method of preventing osteoporotic hip fractures, and is associated with significant adverse effects. Safer, less expensive options exist for preventing fracture in high-risk women.

www.aafp.org/afp/2012/0215/p334.html

STEPS: Dabigatran (Pradaxa) for Prevention of Stroke in Atrial ...

Dec 15, 2011 - Dabigatran is superior to warfarin for stroke prevention in patients with atrial fibrillation, with similar rates of major bleeding. Because it does not require laboratory monitoring, dabigatran therapy is less ...

www.aafp.org/afp/2011/1215/p1397.html

STEPS: Tranexemic Acid (Lysteda) for Cyclic Heavy Menstrual ...

Oct 15, 2011 - Tranexamic acid is a nonhormonal option that reduces menstrual blood loss and improves quality of life in patients with heavy menstrual bleeding. It is more expensive than nonsteroidal anti-inflammatory drugs and ...

www.aafp.org/afp/2011/1015/p883.html